Investigator-Initiated Studies

Please contact the Orthopaedic Research Office (604-806-8743) for more information.

Acutrak Study  CURRENTLY RECRUITING

Start Date: March 13, 2017
Principal Investigator: Dr. Alastair S.E. Younger
Sponsor: Acumed

Purpose: This prospective pivotal study aims to assess and compare the efficacy of fully and partially threaded screws, used in subtalar fusion, to create bridging bone.

Biocartilage Study  CURRENTLY RECRUITING

Start Date: January 29, 2019
Principal Investigator: Dr. Andrea Veljkovic
Sponsor: Arthrex

Purpose: The purpose of this study is to evaluate the efficacy of BioCartilage® in the microfracture treatment of osteochondral defects (OCD).

OCD Database Study  CURRENTLY RECRUITING

Start Date: March 28, 2017
Principal Investigator:  Dr. Andrea Veljkovic

Purpose: This study aims to analyze the long term effects of surgical treatment for patients with OCDs. We hope to identify the risk factors of re-operations; to explore any predictors of surgical outcome; and to recognize patients at high-risk for developing OCDs.

OCD Validation Study  RECRUITMENT CLOSED

Start Date: July 22, 2013
Principal Investigator:  Dr. Kevin Wing

Purpose: To gather evidence to support and justify the use of two questionnaires (AOS, FAAM) in the assessment of the different interventions available for treatment of OCD. Ultimately, this study will help to establish a prospective clinical database at the St. Paul’s Hospital Orthopaedic Research Office for use in future OCD research.

OCD Weight Bearing Study  RECRUITMENT CLOSED

Start Date: September 6, 2013
Principal Investigator:  Dr. Alastair Younger

Purpose: To evaluate the effect of weight bearing as tolerated compared to non-weight bearing on patient outcomes following arthroscopic forage of OCDs in the ankle.

Hallux Valgus Education Study  RECRUITMENT CLOSED

Start Date: February 22, 2017
Principal Investigator:  Dr. Andrea Veljkovic

Purpose: To evaluate the effect of an education program on the expectations, satisfaction, and outcomes of patients presenting as first time referrals for Hallux Valgus/Bunions at the St. Paul’s Foot and Ankle Clinic.


Academic Studies

Please contact the Orthopaedic Research Office (604-806-8743) for more information.

COFAS – Ankle Arthritis Study  CURRENTLY RECRUITING

Start Date: April 1, 2003
Investigators:
Dr. Kevin Wing, Dr. Murray Penner, Dr. Alastair Younger

Purpose:To examine the outcomes of ankle fusions and replacements over time. Baseline follow-up scores from 700 patients are analysed to determine the long-term outcomes of ankle fusions and replacements.

SCOPE Study  RECRUITMENT CLOSED

Start Date: June 24, 2014
Investigators: Dr. Alastair Younger, Dr. Murray Penner, Dr. Kevin Wing

Purpose: The primary purpose of this single-centre study is to determine the benefit of arthroscopic surgery vs. open surgery for indications in foot surgery.

WEDGE II Study  CURRENTLY RECRUITING

Start Date: January 1, 2016
Principal Investigator:  Dr. Alastair Younger

Purpose: To evaluate distal tibial osteotomies as a treatment option for arthritis or deformity of the ankle compared to ankle arthroplasty and arthrodesis.


Sponsored Studies

Please contact the Orthopaedic Research Office (604-806-8743) for more information.

Biocomposites Stimulan  CURRENTLY RECRUITING

Start Date: December 10, 2019
Investigators: Dr. Alastair Younger, Dr. Kevin Wing, Dr. Murray Penner, Dr. Andrea Veljkovic
Sponsor: Biocomposites

Purpose: The purpose of this study is to evaluate the efficacy of Stimulan Rapid Cure Bone Void Filler in bone formation and regeneration, as well as in preventing/treating infection after transmetatarsal amputation, with two antibiotic concentrations.

Zimmer Subchondroplasty Study  CURRENTLY RECRUITING

Start Date: March 22, 2018
Investigators: Dr. Alastair Younger, Dr. Kevin Wing, Dr. Murray Penner, Dr. Andrea Veljkovic
Sponsor: Zimmer Inc.

Purpose: To collect data on the short- and long-term outcomes for subjects who are undergoing or who have undergone the Subchondroplasty procedure in the foot and/or ankle in a standard clinical setting. Outcomes to be assessed include medication usage, pain, function, health status and patient satisfaction.

Zimmer Trabecular Metal Total Ankle Study  RECRUITMENT CLOSED

Start Date: August 1, 2014
Investigators: Dr. Alastair Younger, Dr. Kevin Wing, Dr. Murray Penner, Dr. Andrea Veljkovic
Sponsor: Zimmer Inc.

Purpose: This study is intended to evaluate the safety and performance of the Zimmer Trabecular Metal Total Ankle in treating patients with severe pain and disability from end-stage ankle arthritis.