Research for the Division of Lower Limb Reconstruction & Oncology
The BC Foot and Ankle Clinic, St. Paul’s Hospital
Dr. Alastair Younger (Head), Dr. Kevin Wing and Dr. Murray Penner

Research Coordinator/Manager: Biraj Bora

Research Assistants: Alex Ho, Jolina Carson

Accountant: MaryAnn Kwong

Volunteers: Christopher O'Grady, Hailey Jung, Jennifer Dhammi, Stephanie Wong, Jenna Wong, Kevin, Ian Le, Sijia, Ghazel, Tim...

COFAS Ankle Arthritis Surgical Outcome Study:
The BC Foot and Ankle Research Office is currently gathering long-term follow-up data to compare the surgical outcomes of ankle arthrodesis (fusion) and total ankle arthroplasty (replacement).  This study has been ongoing for approx. 3 years, and it will continue to be a prime focus of Foot and Ankle Research in the next few years (Investigators: Dr. Alastair Younger, Dr. Murray Penner, Dr. Kevin Wing, Research Coordinator: Biraj Bora, Research Assistants: Alex Ho, Joanie Maynard, and Liz Hendren).

A Human Clinical Trial to Evaluate the Clinical Utility of GEM OS1 as a Bone Regeneration Device in Foot and Ankle Arthrodesis Procedures (Sponsor - BioMimetic Pharmaceuticals Inc., Principal Investigator: Dr. Alastair Younger, Co Investigators: Dr. Murray Penner, Dr. Kevin Wing, Research Coordinator: Biraj Bora)

A Prospective, Randomized, Controlled, Multi-Center Pivotal Human Clinical Feasibility Trial to Evaluate the Safety and Effectiveness of GEM OS1^™ Compared to Autologous Bone Graft as a Bone Regeneration Device in Foot and Ankle Fusions (Sponsor - BioMimetic Pharmaceuticals Inc., Principal Investigator: Dr. Alastair Younger, Co Investigators: Dr. Murray Penner, Dr. Kevin Wing, Research Coordinator: Biraj Bora)

A Prospective, Randomized, Controlled, Multi-Center, Pivotal Human Clinical Trial to Evaluate the Safety and Effectiveness of AIBG ™ Compared to Autologous Bone Graft as a Bone Regeneration Device in Foot and Ankle Fusions ((Sponsor - BioMimetic Pharmaceuticals Inc., Principal Investigator: Dr. Alastair Younger, Co Investigators: Dr. Murray Penner, Dr. Kevin Wing, Research Coordinator: Biraj Bora)

A Multicenter, Randomized, Double-Blind, Comparison Study of the Safety and Efficacy of a Once-Daily Dose of Tigecycline Versus Ertapenem for the treatment of Foot Infections in Subjects with Diabetes. (Sponsor - WYETH Research, Principal Investigator: Dr. T.C. Yang, Co Investigators: Dr. Tim Kalla, Dr. Alastair Younger, Dr. Gavin Chalmers, Dr. Ian Yu, Research Coordinator: Biraj Bora)

A PHASE 2, MULTICENTER, DOUBLE-BLIND, RANDOMIZED, STRATIFIED, CONTROLLED, EFFICACY, SAFETY AND FEASIBILITY STUDY OF rhBMP-2/CPM AS AN ADJUVANT THERAPY IN CLOSED FRACTURES OF THE HUMERUS (Sponsor - WYETH Research, Principal Investigator: Dr. Donna Smith, Co Investigator: Dr. Tom Goetz, Research Coordinator: Biraj Bora)

A Prospective, Randomized, Non-Inferiority Study to Evaluate the Effectiveness of Cartiva™ Synthetic Cartilage Implant in the Treatment of First Metatarsophalangeal Joint Osteoarthritis as Compared to a Control - Cartiva MOTION Study (Sponsor - Carticept Medical, Principal Investigator: Dr. Alastair Younger, CoInvestigators: Dr. Murray Penner, Dr. Kevin Wing, Research Coordinator:  Biraj Bora)

A Prospective, Pilot, Single-Center, Human Clinical Trial Comparing the Effectiveness of Operative versus Non-Operative Procedures in the Treatment of Metacarpal Fractures. (Principal Investigators: Dr. Sean Bristol, Dr. Andrew Tung, Dr. Neil Wells, Dr. Thomas Goetz, Research Coordinators: Biraj Bora and Jolina Carson)

Global Ankle Arthroscopy: A Prospective Study to Compare the Complication Rates reported for Arthroscopy using a Posteromedial Portal to the Complication Rates in the literature for Posteromedial and Standard Ankle Arthroscopy Portals. (Principal Investigator: Dr. Alastair Younger, Co-investigator: Dr. Heather Barske,Research Coordinators: Biraj Bora and Jolina Carson)

For more information, contact the BC Foot and Ankle Clinical Research Coordinator, Biraj Bora: (604) 806-8743.

Research Office is located at:

1081 Burrard St., 3rd Floor Burrard Bldg, Rm. 306C, Vancouver, V6Z 1Y6